Chris Masterjohn (substack, Harnessing the power of nutrients) posted an interesting article on niacin, which seems to agree with your views. You might have a look.
Just tried to read this above article - much difficulty in comprehension, but the bottom line is, do not exceed 250 mg a day, on a short term fix something agenda. I think my taking 500 mg for two years is a bit too much.
That was my issue with the study. They never said what the amounts were, what forms niacin was in, was it from whole food, processed food or supplements.
I've been taking 500 mg of niacin (NiaVasc) for 2 years now, from my doctor's recommendation, for high cholesterol. After reading the first part of your article, I thought perhaps i should stop taking it, because it wasn't lowering my cholesterol, and now there was a possibility it might harm my heart. I was very interested in reading the rest of your article today. Perhaps niacin isn't damaging, but it doesn't seem to be helping, in my case.
I still think based on some previous studies that niacin can be useful for people with elevated lp (a), a gentic CVD marker that a statin would have no effect on. Allopathic doctors do not usually run this test since they do not have a drug that can reduce this marker.
As I have posted in prior substacks, what is high cholesterol? TC numbers were reduced when statins came to market and meant a whole new part of the population could be placed on these meds. A general lipid panel will not tell you much. Look at how high the HDL is in conjunction with fasting insulin (doctors do not run this marker as often either) and get an advanced lipid panel that looks at lipid particle size. Another useful option is the calcium artery scan.
Chris Masterjohn (substack, Harnessing the power of nutrients) posted an interesting article on niacin, which seems to agree with your views. You might have a look.
https://chrismasterjohnphd.substack.com/p/nmn-probably-wont-make-you-live-forever?open=false
Just tried to read this above article - much difficulty in comprehension, but the bottom line is, do not exceed 250 mg a day, on a short term fix something agenda. I think my taking 500 mg for two years is a bit too much.
He writes a little above my level, but that was my understanding too.
Yes, Masterjohn is very technical and can be challenging to comprehend. The Mercola article also appears to align with a lower dose for CVD.
I don't have time to read the study at the moment but... what type of niacin were they using? There seems to be a difference in the effects.
That was my issue with the study. They never said what the amounts were, what forms niacin was in, was it from whole food, processed food or supplements.
I've been taking 500 mg of niacin (NiaVasc) for 2 years now, from my doctor's recommendation, for high cholesterol. After reading the first part of your article, I thought perhaps i should stop taking it, because it wasn't lowering my cholesterol, and now there was a possibility it might harm my heart. I was very interested in reading the rest of your article today. Perhaps niacin isn't damaging, but it doesn't seem to be helping, in my case.
I still think based on some previous studies that niacin can be useful for people with elevated lp (a), a gentic CVD marker that a statin would have no effect on. Allopathic doctors do not usually run this test since they do not have a drug that can reduce this marker.
As I have posted in prior substacks, what is high cholesterol? TC numbers were reduced when statins came to market and meant a whole new part of the population could be placed on these meds. A general lipid panel will not tell you much. Look at how high the HDL is in conjunction with fasting insulin (doctors do not run this marker as often either) and get an advanced lipid panel that looks at lipid particle size. Another useful option is the calcium artery scan.
Thank you yet you left out Brazil nuts. "A single serving of Brazil nuts can dramatically lower LDL cholesterol level in a matter of hours. “LDL, so-called “bad” cholesterol levels in the blood, was significantly lower starting just nine hours after the ingestion of nuts, and by no insignificant amount, nearly 20 points within a day. Even drugs don’t work that fast. It takes statins around four days to have a significant effect.” https://www.researchgate.net/publication/248385213_A_Single_Consumption_of_High_Amounts_of_the_Brazil_Nuts_Improves_Lipid_Profile_of_Healthy_Volunteers
Thank you for sharing that information Jim.
Thank you for the link.