Some of these dosages are in the mega-dose range. Are any of them high enough that you would need to monitor with blood testing, or watch for symptoms of toxicity?
As stated in the article, if on blood thinners, you would need to be monitored and tested by prescribing doctor. Also, much depends on the health prior to the concussion. For instance, someone who was eating a very inflammatory diet may need the high doses of fish oil, blueberry extract and so forth whereas someone else eating a Whole Foods diet may not. It should be tailored to the individual which will determine testing. Therapeutic doses should only be used short term, monitored and then reassessed. Always good to have recent biomarker information such as CRP, omega status, vitamin D.
I'm sorry, I should have been more specific. The magnesium dosage is the one that caught my attention. A few years ago my daughter had breast cancer, and chose conventional cut, burn and poison therapy, but I also had her taking quite a few supplements - some good cancer fighters and others to mitigate the chemo side effects. At one point she began having neuropathy symptoms - sharp, shooting pains originating in her fingertips. 800 mg/day of magnesium quickly resolved this, but soon after that she began having heart palpitations. We stopped the magnesium until that went away, and then resumed a lower dose (400mg/day). IIRC, the magnesium was a chelated form, most likely either citrate or aspartate. I'm pretty sure it was not L-threonate. Both dosages were much lower than the recommendation of 1-2 grams for brain injuries, yet it seemed like she was experiencing some toxicity issues. Could the form of magnesium or the chemo drug have affected how she reacted to the magnesium?
Difficult for me to say. Low and high mag amount can present those symptoms and chemo can also cause those symptoms. My guess would be if going through chemo, she was deficient. Again, short term in higher doses to avoid toxicity and individualized. I may use a higher dose for one person and a much lower dose for another person. You can alway do serum or RBC magnesium testing to have a baseline.
Thanks for some very useful information.
Some of these dosages are in the mega-dose range. Are any of them high enough that you would need to monitor with blood testing, or watch for symptoms of toxicity?
As stated in the article, if on blood thinners, you would need to be monitored and tested by prescribing doctor. Also, much depends on the health prior to the concussion. For instance, someone who was eating a very inflammatory diet may need the high doses of fish oil, blueberry extract and so forth whereas someone else eating a Whole Foods diet may not. It should be tailored to the individual which will determine testing. Therapeutic doses should only be used short term, monitored and then reassessed. Always good to have recent biomarker information such as CRP, omega status, vitamin D.
I'm sorry, I should have been more specific. The magnesium dosage is the one that caught my attention. A few years ago my daughter had breast cancer, and chose conventional cut, burn and poison therapy, but I also had her taking quite a few supplements - some good cancer fighters and others to mitigate the chemo side effects. At one point she began having neuropathy symptoms - sharp, shooting pains originating in her fingertips. 800 mg/day of magnesium quickly resolved this, but soon after that she began having heart palpitations. We stopped the magnesium until that went away, and then resumed a lower dose (400mg/day). IIRC, the magnesium was a chelated form, most likely either citrate or aspartate. I'm pretty sure it was not L-threonate. Both dosages were much lower than the recommendation of 1-2 grams for brain injuries, yet it seemed like she was experiencing some toxicity issues. Could the form of magnesium or the chemo drug have affected how she reacted to the magnesium?
Difficult for me to say. Low and high mag amount can present those symptoms and chemo can also cause those symptoms. My guess would be if going through chemo, she was deficient. Again, short term in higher doses to avoid toxicity and individualized. I may use a higher dose for one person and a much lower dose for another person. You can alway do serum or RBC magnesium testing to have a baseline.